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Redefining HealthcareAround You.
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Treated Conditions

AVM (Arteriovenous Malformation)
Blurry Vision
Carotid and Vertebral Artery Dissection
Cavernous Malformation
Circadian Rhythm Disorders
Cognitive Changes

Research and Clinical Trials

Neuroscience research at Carle represents the intersection of technology, medicine, science, and care. By providing our patients with the opportunity to participate in translational and clinical studies we hope to engage them in not only their own care but also the future of medicine. Our researchers and providers strive to advance diagnostic capabilities, understand causes and effects, and improve patient quality of life. Our research department supports clinicians and faculty alike in their efforts to provide excellent care and perform extraordinary science.

By participating in research studies, Carle Neuroscience Institute seeks to create a better understanding of the structure and function of neurological systems allowing us to advance clinical care possible and ultimately improve the overall promotion of human health and quality of life.

Carle Neuroscience Institute Research is known for demonstrating improved clinical outcomes for patients through research efforts that focus on the development of predictive analysis, novel diagnostics, and comparative efficacy.

Study of Perampanel as Adjunctive Treatment for Inadequately Controlled Seizures Associated With Lennox-Gastaut Syndrome

This study is being conducted to demonstrate that perampanel given as adjunctive anti-epileptic treatment is superior to placebo in reducing the number of drop seizures in participants with inadequately controlled seizures associated with Lennox-Gastaut Syndrome (LGS)

P-15L Bone Graft in Transforaminal Lumbar Interbody Fusion With Instrumentation

The aim of this trial is to evaluate if P-15L bone graft (investigational device) is not inferior in effectiveness and safety to local autologous bone (and allograft where necessary) as an extender (control device) when applied in instrumented transforaminal lumbar interbody fusion (TLIF) in subjects with degenerative disc disease (DDD). In addition to the general overall objective, a sub-group analysis will be performed on the high-risk subject population (tobacco use, obesity, diabetes), as previous studies have shown negative effects of smoking, obesity and diabetes on fusion and bone healing, increased peri/postoperative complications, and lower patient-reported outcome scores

A Pivotal Study of the Premia Spine TOPS™ System

The purpose of this trial is to assess whether the Total Posterior Spine System (TOPS System) is more effective than transforaminal lumbar interbody fusion (TLIF) when used to stabilize a single lumbar level (L2 - L5) following surgical decompression in patients diagnosed with (1) at least moderate lumbar spinal stenosis, and (2) Grade 1 spondylolisthesis (or retrolisthesis), and (3) thickening of the ligamentum flavum or scarring of the facet joint capsule.

SEE MORE CLINICAL TRIALS

Meet Our Team

With doctors practicing in 80 specialties at locations throughout the region, it’s easy to find the right healthcare team at Carle. Our mission is to serve people through high quality care, medical research and education.

MEET OUR TEAM

Giving

Charitable gifts are used for numerous projects and programs that enhance the healthcare experience for Carle patients and their loved ones. With your support, we’ll advance the care of neurological diseases and meet the needs of the 
ever-expanding Carle Neuroscience Institute.

DONATE NOW GIVING AT CARLE

Awards and Accreditations

Recognized among the nation’s top hospitals, Carle provides excellent healthcare while continuously improving to meet the needs of our patients.

    • GL Accredited Hospital
    • Healthgrades logo
    • Get with the guidelines - 2018 gold plus certified